I.C. Learning & Memory
Gina R Poe
The Poe lab searches for mechanisms whereby sleep serves memory consolidation in health and disorders of cognition and emotion. We use a combination of multiple single unit recordings, optogenetics, miniscope Ca++ imaging, behavioral tasks, and other tools in rats, mice and sometimes humans to learn the sleep traits, neural circuits, neurotransmitters, and states that are critical for learning and remodeling our memories with experience.
Recent Publications:
Swift, K.M., K. Keus, C.G. Echeverria, Y. Cabrera, J. Jimenez, J. Holloway, B.C. Clawson, and G.R. Poe, Sex differences within sleep in gonadally intact rats. Sleep, 2020. 43(5).
Swift, K.M., B.A. Gross, M.A. Frazer, D.S. Bauer, K.J.D. Clark, E.M. Vazey, G. Aston-Jones, Y. Li, A.E. Pickering, S.J. Sara, and G.R. Poe, Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory. Curr Biol, 2018. 28(22): p. 3599-3609 e4.
Poe, G.R., Sleep Is for Forgetting. J Neurosci, 2017. 37(3): p. 464-473.
Lewis, P.A., G. Knoblich, and G. Poe, How Memory Replay in Sleep Boosts Creative Problem-Solving. Trends Cogn Sci, 2018. 22(6): p. 491-503.
Guthrie, R.S., D. Ciliberti, E.A. Mankin, and G.R. Poe, Recurrent Hippocampo-neocortical sleep-state divergence in humans. Proc Natl Acad Sci U S A, 2022. 119(44): p. e2123427119.
Gross, B.A., W.M. Vanderheyden, L.M. Urpa, D.E. Davis, C.J. Fitzpatrick, K. Prabhu, and G.R. Poe, Stress-free automatic sleep deprivation using air puffs. J Neurosci Methods, 2015. 251: p. 83-91.
Emrick, J.J., B.A. Gross, B.T. Riley, and G.R. Poe, Different Simultaneous Sleep States in the Hippocampus and Neocortex. Sleep, 2016. 39(12): p. 2201-2209.
Corsi-Cabrera, M. and G.R. Poe, The role of sleep in processing emotional and contextual information: from mechanism to impact on everyday life and emotional health. Exp Brain Res, 2014. 232(5): p. 1399-401.
Cao, J., A.B. Herman, G.B. West, G. Poe, and V.M. Savage, Unraveling why we sleep: Quantitative analysis reveals abrupt transition from neural reorganization to repair in early development. Sci Adv, 2020. 6(38).
Cabrera, Y., J. Holloway, and G.R. Poe, Sleep Changes Across the Female Hormonal Cycle Affecting Memory: Implications for Resilient Adaptation to Traumatic Experiences. J Womens Health (Larchmt), 2020. 29(3): p. 446-451.
Bjorness, T.E., V. Booth, and G.R. Poe, Hippocampal theta power pressure builds over non-REM sleep and dissipates within REM sleep episodes. Arch Ital Biol, 2018. 156(3): p. 112-126.
