Tom Minor's laboratory is using behavioral and pharmacological tools to study stress and stress resilience in humans and animals. They also study animal models of anxiety, depression, and attention disorders, as well as fundamental properties of conditioning and learning.
Vulnerability factors in anxiety: Strain and sex differences in the use of signals associated with non-threat during the acquisition and extinction of active-avoidance behavior. Beck KD, Jiao X, Ricart TM, Myers CE, Minor TR, Pang KC, Servatius RJ., Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15;35(7):1659-70. Epub 2011 May 13.
Avoidance perseveration during extinction training in Wistar-Kyoto rats: an interaction of innate vulnerability and stressor intensity. Jiao X, Pang KC, Beck KD, Minor TR, Servatius RJ. Behav Brain Res. 2011 Aug 1;221(1):98-107. Epub 2011 Mar 2.
Biochemical and anatomical substrates of depression and sickness behavior. Hanff TC, Furst SJ, Minor TR. Isr J Psychiatry Relat Sci. 2010;47(1):64-71. Review.
Enhancing brain adenosine signaling with the nucleoside transport blocker NBTI (S-(4-nitrobenzyl)-6-theoinosine) mimics the effects of inescapable shock on later shuttle-escape performance in rats. Minor TR, Rowe M, Cullen PK, Furst S. Behav Neurosci. 2008 Dec;122(6):1236-47.
Rapid avoidance acquisition in Wistar-Kyoto rats. Servatius RJ, Jiao X, Beck KD, Pang KC, Minor TR. Behav Brain Res. 2008 Oct 10;192(2):191-7. Epub 2008 Apr 18.