Kelsey Martin's lab is studying the mechanisms of synaptic plasticity with a focus on intra-neuronal signaling, and mRNA localization and regulated translation. The goal is to understand how these molecular and cellular processes affect memory formation and consolidation.
Spatially restricting gene expression by local translation at synapses.
Wang, D.O., Martin, K.C. and Zukin, R.S.
Trends Neurosci. 33, 173-182, 2010.
Anchoring local translation in neurons.
Cell. 141, 566-568, 2010.
Regulated expression of the Ras effector Rin1 in forebrain neurons.
Dzudzor B, Huynh L, Thai M, Bliss JM, Nagaoka Y, Wang Y, Ch’ng TH, Jiang M, Martin KC, and Colicelli J.
Mol Cell Neurosci. 43, 108-116, 2010.
Activity-dependent anchoring of importin alpha at the synapse involves regulated binding to the cytoplasmic tail of the NR1-1a subunit of the NMDA receptor.
Jeffrey RA, Ch’ng TH, O’Dell TJ, and Martin KC.
J Neurosci. 29, 15613-15620, 2009.
Synapse- and stimulus-specific local translation during long-term neuronal plasticity.
Wang DO, Kim SM, Zhao Y, Hwang HG, Miura SK, Sossin WS, and Martin KC.
Science. 324, 1536-1540, 2009.