Franklin Krasne's lab uses the neural circuitry that mediates escape behavior in the crayfish as a model system to investigate factors that modulate the likelihood of behavioral actions. These include habituation due to repetitive stimulation and modulation during competing activities such as feeding and fighting. His lab is also interested in developing computational models of fear learning mechanisms.
Design of a neurally plausible model of fear learning.
Krasne FB, Fanselow MS, Zelikowsky M.
Front Behav Neurosci. 2011;5:41. Epub 2011 Jul 26.
Reciprocal stimulation of decay between serotonergic facilitation and depression of synaptic transmission.
Lee SH, Taylor K, Krasne FB.
J Neurophysiol. 2008 Aug;100(2):1113-26. Epub 2008 Jun 18.
Rostral ganglia are required for induction but not expression of crayfish escape reflex habituation: role of higher centers in reprogramming low-level circuits.
Shirinyan D, Teshiba T, Taylor K, O'Neill P, Lee SC, Krasne FB.
J Neurophysiol. 2006 Apr;95(4):2721-4. Epub 2005 Dec 28.
Metamodulation of the crayfish escape circuit.
Edwards DH, Yeh SR, Musolf BE, Antonsen BL, Krasne FB.
Brain Behav Evol. 2002;60(6):360-9.
Modulation of the crayfish escape reflex--physiology and neuroethology.
Krasne FB, Edwards DH.
Integr Comp Biol. 2002 Aug;42(4):705-15.
PMID: 21708767 [PubMed - in process] Free Article